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Description:
This course provides a direct continuation of Organic Chemistry I (CHEM-202) and develops and extends many of the concepts and approaches developed therein. Topics include stereochemistry, substitution and elimination reactions, conformational analysis, addition reactions of multiple bonds, substitution reactions of aromatic systems, and a broad extension of the carbonyl chemistry introduced in the preceding class. Consideration will be given to the development of organic syntheses of specific materials and attendant issues of compatibility and selectivity in reaction choice. The scope and reach of the spectroscopic methods introduced in Organic Chemistry I will be extended and applied to structure determination. The accompanying laboratory course provides additional practice with the techniques of preparation, isolation, purification, and chemical and spectroscopic analysis of organic compounds. Mechanistic interpretation of results, in-depth analysis of spectroscopic data, and the development of synthetic protocols are areas of special emphasis.
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